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Opioid ReceptorGABA System
7-OH vs Kava: Complete Relaxation Comparison
Two powerful natural relaxants with completely different mechanisms. Compare 7-hydroxymitragynine (opioid pathway) to kava (GABA pathway) for anxiety, pain, and stress relief.
7-Hydroxymitragynine
Opioid Receptor Agonist
- Strong pain relief
- Euphoric mood lift
- Energy at low doses
- Tolerance builds quickly
- Withdrawal possible
Kava
GABA Modulator
- Excellent for anxiety
- Muscle relaxation
- Lower addiction potential
- Weak for pain
- Liver concerns (rare)
Side-by-Side Comparison
| Use Case | 7-OH | Kava |
|---|---|---|
| Anxiety Relief | Good | Excellent |
| Pain Relief | Excellent | Mild |
| Sleep Support | Good (high dose) | Very Good |
| Social Situations | Good | Excellent |
| Daily Use Safety | Moderate Risk | Lower Risk |
| Addiction Potential | Higher | Lower |
Different Mechanisms, Different Effects
7-OH works primarily through mu-opioid receptors, producing effects similar to (but distinct from) traditional opioids. This makes it excellent for pain relief but carries risks of tolerance and physical dependence with regular use.
Kava works through the GABA system, similar to benzodiazepines but without the same addiction profile. Kavalactones produce anxiolytic and muscle-relaxing effects that are ideal for stress and anxiety but offer little in terms of analgesia.
Choose 7-OH If You Need:
- Strong pain relief for chronic conditions
- Energy and mood enhancement
- Opioid withdrawal support
- Potent, fast-acting effects
Choose Kava If You Need:
- Anxiety relief without opioid effects
- Social relaxation (alcohol alternative)
- Gentle sleep support
- Lower-risk daily use option
Shop 7-OH Products
Lab-tested 7-hydroxymitragynine products